Transcript

A camera slowly zooms in on a woman sitting up on a bed in the middle of a suburban street. The camera cuts to the woman’s face as she is in a state of thought. As she gets out of bed, the scene changes to inside her home.

FOR BIPOLAR I & II DEPRESSION IN ADULTS. Actor Portrayals

Available by prescription only. CAPLYTA is not approved for people under 18.

The darkness of bipolar depression made me feel like I was losing interest in the things I love.

The woman stands inside and opens the window curtains to look outside on the sunny day.

ONCE-DAILY [CAPLYTA^® (lumateperone) capsules logo]

[LET IN THE LYTE logo]

Available by prescription only. CAPLYTA is not approved for people under 18.

Then I found a chance to Let in the Lyte.

The woman continues to look out the window curtains to look outside on a bright day. A small child, her daughter, comes into the room and smiles at the woman. The mother and child begin holding hands.

ONCE-DAILY [CAPLYTA^® (lumateperone) capsules logo]

[LET IN THE LYTE logo]

Available by prescription only. CAPLYTA is not approved for people under 18.

Discover CAPLYTA. Unlike some medicines that only treat bipolar I and II,

The mother and child walk outside and down the front porch, still holding hands. Cut to the woman and child walking through a park with the father figure, who is walking a dog.

ONCE-DAILY [CAPLYTA^® logo]

SIGNIFICANT RELIEF FROM BOTH BIPOLAR I & II DEPRESSION.

Can be taken alone or with lithium or valproate.

CAPLYTA is proven to deliver significant symptom relief from both bipolar I and II depression.

The mother and child continue to hold hands and walk together through the town together.

ONCE-DAILY [CAPLYTA^® logo]

IN CLINICAL TRIALS

• - MOVEMENT DISORDERS
• - WEIGHT GAIN

WERE NOT COMMON

High cholesterol and weight gain may occur, as can high blood sugar which may be fatal.

Monitoring is recommended.

And in clinical trials, movement disorders and weigh gain were not common.

The mother and child enter a bakery shop and purchase a cupcake for the child. The family then continues their walk through a local park.

[CAPLYTA^® logo]

FOR BIPOLAR I & II DEPRESSION

CAPLYTA can cause serious side effects. Call your doctor about sudden mood changes,

behaviors, or suicidal thoughts right away. Anti-depressants may increase these risks in young

adults. Elderly dementia patients have an increased risk of death or stroke. CAPLYTA is not

approved for dementia-related psychosis.

CAPLYTA can cause serious side effects. Call your doctor about sudden mood changes, behaviors, or suicidal thoughts right away. Anti-depressants may increase these risks in young adults. Elderly dementia patients have increased risk of death or stroke. CAPLYTA is not approved for dementia-related psychosis.

The family continues their walk together through the park, over a small bridge, and then sits down to enjoy a picnic in the park.

[CAPLYTA^® logo]

FOR BIPOLAR I & II DEPRESSION

Report fever, confusion, or stiff muscles, which may be life-threatening, or uncontrolled muscle

movements which may be permanent. Common side effects include sleepiness, dizziness,

nausea, and dry mouth. These aren’t all the side effects.

Report fever, confusion, or stiff muscles, which may be life-threatening, or uncontrolled muscle

movements which may be permanent. Common side effects include sleepiness, dizziness,

nausea, and dry mouth. These aren’t all the side effects.

The father teaches the child how to ride a bike down their quiet suburban street.

[CAPLYTA^® logo]

FOR BIPOLAR I & II DEPRESSION

To learn more, go to CAPLYTA.com or call 888-252-4824.

In the darkness of bipolar I and II depression, CAPLYTA can help you Let in the Lyte. Ask your

doctor about CAPLYTA.

The camera quickly cuts to a blue screen with the CAPLYTA logo, a QR code, and copy about

prescription savings. The ITCI logo is present at the bottom of the screen with adjacent on-screen text.

[CAPLYTA^® logo]

[QR code] ELIGIBLE PATIENTS PAY AS LITTLE AS $0 FOR THEIR FIRST TWO

PRESCRIPTIONS

[Intra-Cellular Therapies logo]

Terms and Conditions and Eligibility Criteria at CAPLYTA.com. Visit CAPLYTA.com for product

and pricing information.

Find savings and support at CAPLYTA.com.